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脂蛋白相关磷酯酶A2在急性脑血栓形成诊断中的价值 被引量:5

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摘要 目的探讨脂蛋白相关磷酯酶(Lp-PL)A2对急性脑血栓形成(CT)的诊断价值。方法选取通过病史、症状和体查拟诊为疑似脑CT患者115例,再采用诊断金标准分为脑CT(65例)和非脑CT组(50例),所有研究对象均采用,ELISA法测定Lp-PLA2,采用循证检验医学的方法统计各诊断价值性能指标。结果脑CT组Lp-PLA2为(250.6±145.6)ng/ml,较非脑CT组〔(152.9±59.0)ng/ml〕浓度非常显著升高(P<0.001)。Lp-PLA2对脑CT具有最高诊断效率的诊断界值为173.5 ng/ml,在该界值的诊断灵敏度为67.7%,特异性为84.0%,阳性预测值84.6%,阴性预测值66.7%,阳性似然比4.23,阴性似然比0.38,诊断效率74.8%。根据拟诊率50.5%,计算获得Lp-PLA2对脑CT的诊断概率81.2%,误诊概率18.8%,漏诊概率27.8%,排除概率72.2%。结论单一指标Lp-PLA2对急性脑CT的诊断价值为中等。
出处 《中国老年学杂志》 CAS CSCD 北大核心 2016年第24期6131-6132,共2页 Chinese Journal of Gerontology
基金 佛山市医学类科技攻关项目(201108032) 佛山市培育医学重点专科项目资助(FSPY3-2015022)
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