三维超声对大体积前列腺TURP术中出血的预测价值

Three-dimensional ultrasound predicts the intraoperative blood loss of TURP in large prostate of BPH patients

目的探讨三维能量多普勒超声(3D-PDU)预测大体积前列腺增生(BPH)经尿道前列腺切除术(TURP)术中出血的可行性。方法对34例大体积BPH病人术前进行3D-PDU检查,获得:血管形成指数(VI),血流指数(FI),血管形成-血流指数(VFI);TURP术中记录出血参数;切除标本计数微血管密度(MVD)。比较各参数的相关性。结果 VI、VFI与切除1g前列腺组织出血量、MVD呈正相关(P<0.01);VFI作为预测TURP术中输血的指标,敏感性、特异性分别为0.625、0.962。结论 3D-PDU对评估大体积BPH的血流具有临床意义。

Objective To investigate whether three-dimensional power Doppler Ultrasonography（3D-PDU） can predict the intraoperative bleeding of transurethral resection of the prostate（TURP） in large prostate（〉80m L） of BPH patients. Methods Total of 34 BPH patients with large prostate were enrolled in the study. The vascularization index（VI）, flow index（FI）, vascularization flow index（VFI） were measured using 3D-PDU. All blood parameters associated with blood loss were obtained during surgery. Microvessel density（MVD） were measured using cluster of differentiation 34（CD34） expression. The relationships between 3D-PDU parameters and blood loss parameter, 3D-PDU parameters and MVD were assessed. Results There were positive correlations between VI, VFI and with blood loss of resecting 1g prostate tissue（BL/g）（P 〈0.01）, as well as MVD（P 〈0.01）. The sensitivity and specificity of VFI as the indicators of intraoperative blood transfusion were 0.625 and 0.962, respectively. Conclusion 3D-PDU showed some clinical significance in the assessment of vascularization in large prostate（≥80m L）.