甲状腺次全切除术对结节性甲状腺肿的临床效果分析

Clinical Effect of Subtotal Thyroidectomy for Nodular Goiter

目的研究甲状腺次全切除术对结节性甲状腺肿的临床效果。方法方便选取2012年3月—2015年3月该院收治的80例结节性甲状腺肿患者,随机分为观察组和对照组,对照组患者行甲状腺全切除术治疗,观察组行甲状腺次全切除术治疗,测定记录患者围手术期各项功能指标(手术时间、术中出血量、镇痛剂使用量、住院时间等),术后随访1年,评价两种术式的治疗效果及并发症发生情况,比较组间差异。结果 1观察组镇痛剂用量(82.16±14.82)mg和术中出血量(61.79±16.28)m L显著少于对照组(131.73±19.74)mg、(108.19±25.87)m L,手术时间(56.32±8.64)min、住院时间(9.66±1.01)d明显短于对照组(69.28±9.63)min、(11.93±1.80)d,P<0.05,差异有统计学意义。2观察组有效率33例(82.5%)高于对照组30例(75.0%),但组间比较差异无统计学意义,χ2=0.783,P<0.05。3观察组患者并发症发生率12.5%;对照组为27.5%,显著高于观察组,P<0.05,差异具统计学意义。结论甲状腺次全切除术对结节性甲状腺肿效果显著,围手术期状况明显优于甲状腺全切除术,并发症少,利于患者较快恢复。

Objective To study the clinical effect of subtotal thyroidectomy for nodular goiter. Methods Convenient selection 80 patients admitted from March 2012 to March 2015 with nodular goiter were randomly divided into observation group and control group. Patients in the control group were treated with total thyroidectomy, and the observation group was treated with subtotal thyroidectomy.Determined and record the function index in operation period（operation time, intraoperative blood loss, analgesics usage, and length of hospital stay）, postoperative follow-up and evaluated two kinds of surgical treatment and the incidence of complications and compared between groups differences. Results 1The amount of pain（82.16±14.82）mg and blood loss（61.79 ±16.28）m L of the observation group was significantly less than that of the control group（131.73±19.74）mg,（108.19±25.87）m L, and the operation time（56.32±8.64）min, hospitalization time（9.66±1.01）d were significantly shorter than the control group（69.28±9.63）min,（11.93±1.80）d, P〈0.05, the difference was significant.2Compared with the control group, The efficiency of observation group was 33 cases（82.5%） higher than that of the control group30 cases（75%）, but there was no statistical significance between the two groups, χ2=0.783, P〈0.05.3The incidence of complications in the observation group was 12.5%; while the control group was 27.5%, which was significantly higher than that of the observation group, P〈0.05, the difference was statistically significant. Conclusion The effect of subtotal thyroidectomy on nodular goiter is significant, and the perioperative period is better than total thyroidectomy, with less complications,which is conducive to the rapid recovery of patients.