血尿酸检测在原发性高血压患者中检测的临床意义

Clinical Significance of Serum Uric Acid Detection in Patients with Essential Hypertension

目的探讨血尿酸检测在原发性高血压患者临床检测中的应用价值。方法选取原发性高血压患者78例为观察组;选取同期体检健康自愿参与者78例为对照组。均采用尿酸氧化酶法检测其血尿酸浓度,并进行比较。结果①经统计,观察组不同性别、不同年龄段的血尿酸水平均显著高于对照组,组间差异均有意义(P<0.05)。②经比较,不同高血压等级和不同并发症高血压的血尿酸水平均存在统计学意义(P<0.05)。③经Logistic回归分析显示,年龄、血尿酸升高以及高TC血症是原发性高血压的危险因素,HDL-C则是其保护因素。结论血尿酸水平升高是原发性高血压的主要危险因素,在该病的临床检测中具有显著的应用价值,可为疾病的诊断、治疗以及预后评估提供重要参考。

Objective To investigate the clinical value of detecting the serum uric acid in patients with essential hypertension. Methods 78 patients with essential hypertension in our hospital were selected as the observation group while 78 healthy people with physical examination and voluntary participants from our hospital over the same period were selected as the control group. Both of the two group were tested by uric acid oxidase method to detect the concentration of the serum uric acid and results of the two groups were compared. Results The blood uric acid levels in the observation group were significandy higher than those in the control group and the difference was significant （P 〈0.05） . There was statistical significance in the serum uric acid levels of different blood pressure levels and different complications of hypertension （P 〈0. 05）. Logistic regression analysis showed that age, serum uric acid and high TC were the risk factors of the essential hypertension, and HDL - C was the protective factor. Conclusion The increasing of serum uric acid levels is a major risk factor for the essential hypertension, which has significant application value in the clinical detection of the disease and can provide an important reference for disease diagnosis, treatment and prognosis.