269例周围神经病的初步分析

The Clinical Analysis of 269 Cases with Peripheral Neuropathies

目的分析周围神经病的临床特点。方法收集2010年1月至2015年12月住院的具有完整临床资料的周围神经病患者269例。对疾病诊断、病因、起病形式、首发症状进行回顾性分析,并对3例典型病例(舌下"神经鞘瘤"、嗜伊红肉芽肿伴多血管炎、多灶性运动神经病)资料进行报道。结果 269例周围神经病患者中,男女比例为1.58:1。单根周围神经损害152例(56.51%),最常见为面神经麻痹;末梢神经损害94例(34.94%)。糖尿病引起的周围神经损害84例(31.23%),运动神经元病21例(7.81%)。急性起病多见147例(54.65%)。大部分以肌力减退为首发症状169例(62.82%)。结论糖尿病引起的周围神经损害发病率最高。

Aim To explore the clinical features of 269 cases with peripheral neuropathies. Methods 269 cases with peripheral neuropathies who were hospitalized from January 2010 to January 2015 were analyzed. The clinical data such as the diagnosis and causes of the disease, type of onset, fi rst symptom were retrospectively analyzed. And the three kinds of uncommon disease were reported. Results The proportion of male and female were 1.58：1. Mononeuropathy were 152 cases（56.50%）, the facial palsy was the most common. Multiple peripheral neuropathies were 94 cases（34.94%）. Diabetic multiple peripheral neuropathies were 84 cases（31.23%）. motor neuro diseases were 21 cases（7.81%）. 147 cases（54.65%） of the peripheral neuropathies were acute onset. Muscle strength decreased was the most common fi rst symptom（169 cases, 62.82%）. The hypoglossal nerve ＂neurilemmoma＂, eosinophilic granulomatosis with polyangiitis, and multifocal motor neuropathy were reported and discussed. Conclusion The highest incidence of peripheral neuropathies was the diabetic multiple peripheral neuropathy.