食管癌三维适形/调强放疗剂量与范围的共识与争议

Consensus and controversies on dose and target volume of three-dimensional conformal radiotherapy for esophageal carcinoma

放射治疗是食管癌的主要治疗手段之一,三维适形/调强放疗技术在降低正常组织损伤的同时,实现了肿瘤剂量的提升,也使5年生存率提高到20%以上,已广泛的应用于临床.近年来,国内外对于照射剂量、靶区范围、淋巴结预防照射与否等方面做了大量的研究,本文就以上问题做一综述.

Radiotherpay is the mainstay treatment for esophageal cancer.Three-dimensional conformal radiotherapy（3DCRT） and intensitymodulated radiotherapy have been widely applied in routine clinical work,because they can raise the target dose and reduce the injury to normal tissue,and therefore raise the fiveyear survival rate to20%.In recent years,a number of studies on 3DCRT have been carried out with regard to radiation dose,target volume contour,and preventive lymph node irradiation,and this article will summarize these issues.