放射性粒子支架治疗50例食管恶性狭窄的效果

Effect of radioactive particle stent therapy in 50 cases of patients with esophageal malignant stricture

目的总结50例食管恶性狭窄患者应用放射性核素粒子食管支架的治疗效果。方法选取吉林市北华大学附属医院心胸外科治疗的100例食管恶性狭窄患者,分为放射性核素粒子食管支架组(治疗组)和普通食管支架组(对照组),在内镜引导下,使导丝通过病变段食管,然后在导丝引导下置入支架输送器,确定位置满意后,退出导丝及输送器。结果放射性相关并发症治疗组全部病例生存期内未发现放射性肺炎、骨髓抑制、免疫力减退等。两组间并发症发生率比较,差异无统计学意义(P>0.05)。两组患者在治疗后生存期方面存在差异有统计学意义(P<0.05)。结论在治疗食管恶性狭窄过程中应用放射性粒子支架是有效且安全的。

Objective To summarize the therapeutic effect of radioactive nuclear particles esophagus stent in 50 cases of patients with esophageal malignant stricture. Methods In our department, 100 cases of esphageal malignant stricture were selected and divided into radioactive nuclear particles esophageal stent treatment group（observation group） and ordinary esophageal stent group（control group）.Under the guidance of endoscopy, the guidewire was passed the diseased esophagus,then embedded stent conveyor under the guidance of guide wire, exited the guidewire and conveyor after the location of satisfaction. Results In all cases of observation group radiation related complications were not found in the survival time of the patients with radiation pneumonia, bone marrow suppression, immunity and so on. The incidence of complications between the two groups was compared, the difference was not statistically significant（P〉0.05）. There were statistically significant differences in the survival of the two groups after the treatment（P〈0.05）. Conclusion It is effective and safe to treat patients with esophageal malignant stricture by using the radioactive nuclear particles.