抗菌药物专项整治中药学干预对门诊抗菌药物应用影响研究

Influence study of pharmaceutical intervention on clinical use of antibacterials in outpatient prescriptions during special rectification

目的探讨专项整治过程中我院各项药学干预措施对门诊处方抗菌药物应用情况的影响。方法随机抽取我院2010年、2012年、2014年每年门诊处方1 200张,作为开展抗菌药物专项整治前、中、后的资料,分析抗菌药物应用情况。结果经专项整治,我院门诊患者抗菌药物使用率2012年降至18.08%,2014年降至14.92%;抗菌药物静脉给药比例2012年降至11.52%,2014年为13.41%;联合用药率2012年降至23.04%,2014年降至14.53%;抗菌药物金额占处方总金额的比例2012年降至12.31%,2014年降至9.96%。结论专项整治活动中各项药学干预措施成效显著,改善了门诊处方抗菌药物使用情况,提高了合理用药水平。

Objective To investigate and analyze the influence of pharmaceutical intervention on clinical use of antibacterials in outpatient prescriptions during special rectification.Methods A retrospective analysis was made, 1 200 outpatient prescriptions were randomly selected during 2010,2012 and 2014.The clinical use of antibacterials before,during and after special rectification was compared.Results After the intervetion during special rectification,the rate of outpatient an- tibacterials prescription decreased to 18.08% in 2012 and 14.92% in 2014,the rate of intravenous decreased to 11.52% in 2012 and 13.41% in 2014,the rate of combination decreased to 23.04% in 2012 and 14.53% in 2014,the rate of antimicrobial prescription amount decreased to 12.31% in 2012 and 9.96% in 2014.Conclusion The implementation of special rec- tification and pharmaceutical intervention improved the use of antibacterials in outpatient prescriptions greatly,and it also improved the level of rational use of drugs in our hospital.