实时动态血糖监测系统在老年糖尿病治疗中的应用

Application of Real-Time Glucose Monitoring System in Aged Patients with Type 2 Diabetes

目的:应用实时动态血糖监测系统(RGMS),监测患者血糖变化,指导医生及时调整方案以期达到最佳疗效。方法:96例老年糖尿病患者,采用RGMS监测72h血糖,60例(对照组)采集5时间点指端末梢血测血糖,制定相应治疗方案,2周后再次检测血糖,3月后测糖化血红蛋白(HbA1C)、体质量指数(BMI)。结果:根据RGMS指导用药2周后,早餐前空腹、早餐后、中餐后、晚餐后、睡前血糖值和对照组比分别是(6.9±1.3)vs(6.7±1.9)mmol/L,P>0.05),(8.8±1.5)vs(10.9±1.6)mmol/L(P<0.05),(8.5±1.2)vs(10.3±1.5)mmol/L(P<0.05)、(8.1±1.3)vs(9.9±1.5)mmol/L(P<0.05)、(7.9±2.2)vs(11.6±2.5)mmol/L(P<0.05),3月后HbA1C、体质指数显著下降(P<0.05)。结论:采用RGMS指导用药,明显增强了糖尿病的疗效,减少低血糖的发生。

Objective：To investigate the constructive role of real-time glucose monitoring system（RGMS）in helping to choose more personalized therapeutic program for obtaining best curative effects in aged patients with type 2diabetes.Methods：RGMS was used to monitor blood glucose of 96 patients with type 2diabetes for 72 hours,meanwhile,another 60patients’ fingertip blood（control group）were monitored at 5time points by normal glucometer.The information of blood glucose was obtained for developing a treatment plan.After two-week treatment,glucose levelwas detected again and after three-month treatment,HbA1 Cand BMI were also examined by relevant methods.Results：The glucose values tested before breakfast,after breakfast,after lunch,after dinner and before bedtime after 2weeks treatment guided by RGMS and in control group were（6.9±1.3）vs（6.7±1.9）mmol/L（P〉0.05）,（8.8±1.5）vs（10.9±1.6）mmol/L（P〈0.05）,（8.5±1.2）vs（10.3±1.5）mmol/L（P〈0.05）,（8.1±1.3）vs（9.9±1.5）mmol/L（P〈0.05）and（7.9±2.2）vs（1.6±2.5）mmol/L（P〈0.05）,respectively.Moreover,The HbA1 C and BMI were also decreased significantly in RGMS group than in control group.Conclusion：Theusage of RGMS in guiding medication significantly enhanced the therapeutic results of diabetes and reduced the incidence of hypoglycemia.