胎儿宫内生长受限的研究进展

Research progress of intrauterine growth restriction

近年来越来越多的证据证明低出生体重儿与代谢性疾病密切相关。目前大多数研究仅限于动物模型阶段,其发病机制是胎儿宫内营养受限导致机体适应性改变、影响基因易感性及出生后外界环境共同作用的结果。人类的研究需要大量的随访资料和实验室数据来预防和干扰成年期疾病的发生。

In recent years, more and more evidences shows that low birth weight has been closely related with metabolic disease. At present, most of the researches were limited to animal models stage, its pathogenesis is the limited nutrition lead to changes in the body＇s adaptability, affect the genetic susceptibility and postnatal outcome of combined action of the role of the environment. Human research requires a lot of follow-up data and laboratory data to prevent and interference the happening of adulthood diseases.