小剂量米索前列醇结合利凡诺注射在中孕引产中的应用效果研究

Effect of small doses of misoprostol combined with ethacridine injection on the induction of labor in pregnancy

目的探讨小剂量米索前列醇结合利凡诺注射在中孕引产中的应用效果。方法选择2013年10月至2015年10月收治的86例进行利凡诺羊膜腔内注射的中孕引产孕妇作为研究对象,将其随机分为对照组和观察组。对照组采用主要成分为淀粉的安慰剂结合利凡诺注射,观察组采用小剂量米索前列醇结合利凡诺注射。对两组患者用药后的产程进展情况、宫缩情况、产后出血量等情况进行全面的监护和记录。结果观察组总产程所需时间、产后出血量及不良反应发生率均明显少于对照组,且观察组用药6 h后Bishop评分改善情况明显优于对照组,差异有统计学意义(P<0.05)。结论小剂量米索前列醇结合利凡诺注射在中孕引产中的应用效果显著,值得在临床上推广使用。

Objective To investigate the small dose of misoprostol combined with low-dose injection of rivanol on the induction of labor in pregnancy. Methods Eighty-six patients from September 2014 to September 2015 period within rivanol amniotic injection of induction of labor in pregnant women were selected as research subjects and were randomly divided into control group and observation group. The main component of the control group were treated with placebo starch binding rivanol injection,while the observation group was given small doses of misoprostol combined with ethacridine injection. After treatment, progress of labor,the contractions and postpartum hemorrhage were monitored and recorded. Results The total process time required for patients was significantly less than that in the control group,the postpartum hemorrhage was less than that in the control group,and Bishop score after 6 h of medication in the observation group improvement was significantly better than that of the control group. Conclusion The effect of combination of low-dose misoprostol and rivanol injection application in pregnant is significant,and should be popularized in clinical practice.