臭氧辅助治疗老年带状疱疹后神经痛的临床疗效分析

Analysis of the effect of ozone therapy for elderly patients with postherpetic neuralgia

目的分析臭氧辅助治疗老年带状疱疹后神经痛的临床疗效。方法选取带状疱疹后神经痛患者46例,随机分为2组,对照组给予阿片类药物加神经阻滞治疗,臭氧组在对照组的基础上增加每周2次臭氧自体血及每周2次臭氧皮下注射治疗。比较2组患者出院日视觉模拟评分(VAS)、住院时间、住院期间口服盐酸羟考酮的日最大剂量及出院当日口服盐酸羟考酮的终剂量、住院费用等指标。结果 2组患者出院日VAS评分比较,差异无统计学意义(P>0.05);臭氧组患者住院时间、住院期间口服盐酸羟考酮的日最大剂量及出院当日口服盐酸羟考酮的终剂量、住院费用均显著低于对照组(P<0.05)。结论臭氧辅助治疗带状疱疹后神经痛可以减少患者口服阿片类药物剂量,减少住院时间及住院费用,经济有效。

Objective To evaluate the effects of ozone therapy in the treatment for postherpetic neuralgia in the elderly patients. Methods Forty-six patients suffering from postherpetic neuralgia were randomly divided into control group and ozone group. Twenty-two patients in control group were given analgesic drugs and nerve blocks. On the basis of control group,twenty-four patients in ozone group were administered with ozone autohemotherapy and ozone injection in the skin lesion twice a week. VAS scores on discharge day,hospitalization time,hospitalization costs,the maximum dose of oxycontin a day in hospital and the final dose of oxycontinonon on discharge day were recorded and compared between two groups. Results There was no significant difference between the two groups in VAS scores on discharge day. The hospitalization time and hospitalization costs,the maximum dose of oxycontina a day in hospital and the final dose of oxycontin in ozone group were significantly lower than those in the control group. Conclusions Ozonetherapy could significantly reduce the hospitalization time and costs and the dose of oxycontin in the patients with postherpetic neuralgia,which suggests that ozone therapy is economic and effective for postherpetic neuralgia.