摘要
EB病毒(EBV)是具有致瘤潜能的疱疹病毒,其编码的潜伏性膜蛋白2A(LMP2A)通过多条信号传导通路,参与上皮细胞的转化。EB病毒存在于胃癌组织中,在胃癌的发生和发展过程中发挥重要的作用。本文主要就LMP2A的结构、介导的信号传导通路与胃癌的关系进行综述。
Epstein＇Barr virus is a herpes virus with tumorigenic potential, its encoded latent membrane protein-2A through multiple signaling pathways, involved in the transformation of epithelial cells. The EB virus exists in gastric cancer cells, in the process of the occurrence and development of gastric cancer play an important role. This article mainly reviews the structure of LMP2A, mediated signaling pathway and gastric cancer.
出处
《基层医学论坛》
2016年第32期4585-4586,共2页
The Medical Forum
基金
湖南省自然科学衡阳联合基金(12JJ9033)
关键词
胃癌
EB病毒
潜伏性膜蛋白2A
信号传导通路
Gastric cancer Epstein-Barr virus Latent membrane protein-2A Signaling pathway
