植物过氧化物酶超家族的分子结构

Molecular structure of plant peroxidase superfamily

过氧化物酶广泛存在于生物中。基于序列相似性比较,可将真菌、细菌和植物来源的过氧化物酶归为一个超家族-植物过氧化物酶超家族。作者对近几年来植物过氧化物酶超家族的分子结构与功能研究进展,从过氧化物酶的辅基（血红素）微循环结构、过氧化物酶超家族的序列结构域,以及酶分子中底物结合位点和 Ca2+结合位点的结构等方面作了简要评述。

Peroxidases are heme proteins whose primary function is to oxidize a large variety of substrates at the expense of hydrogen peroxide. It has been proposed, from an extensive comparison among the amino acid sequences, that heme peroxidases from fungi, bacteria and plants are evolutionarily related and constituted a superfamily-plant peroxidase superfamily. Progress of research on molecular structure and function of plant preoxidase superfamily has been briefly reviewed, including the prosthetic group (heme) micro-environment of the peroxidase molecules, the sequence domains of the plant peroxidase superfamily, and the strucutures of substrates binding sites and Ca2+ binding sites in peroxidase molecules.