控制饮食与脊髓亚急性联合变性的相关性研究

The correlation between control diet and subacute combined degeneration of the spinal cord

目的探讨控制饮食在亚急性联合变性发病中的影响作用。方法回顾性分析天津市静海区人民医院55例SCD患者记为SCD组,同期健康体检人员50例为对照组。收集比较两组患者控制饮食情况、血清维生素B1 2值、脊髓MRI及神经电生理检查结果。结果与对照组相比,SCD组中控制饮食者数量明显多于非控制饮食者数量(分别为67.3%,3 2.7%),差异具有统计意义(P<0.05)。对SCD组内饮食控制和非饮食控制进行比较,发现控制饮食者维生素B12水平更低,神经电生理异常明显,差异具有统计意义(P<0.05)。结论控制饮食与SCD具有相关性,是SCD发病的影响因素;有必要深入调查脑血管病患者存在控制饮食过度严格的问题。

Objective To investigate the influence of control diet in subacute combined degeneration pathogenesis.Methods A retrospective analysis in Tianjin jinghai District people＇s hospital of 55 SCD patients as the patient group,50 healthy volunteers in the same period as the control group,and collect their control diet,serum vitamin B_（12） value,spinal MRI and neurophysiological findings.Results To compare with patients in the control group,the ones who control diet were significantly more in SCD group（67.3%,32.7%respectively）.The difference was statistically significant（p0.05）.Among the SCD group,patients who control their diet had lower level Vitamin B_（12） and more neurophysiological abnormalities（P〈0.05）.Conclusion Control diet is relevant with SCD,and the important factor in pathogenesis of SCD.It is necessary to investigate state of diet overcontrolled.in patients with cerebrovascular diseases.