幼年系统性硬皮病的研究进展

Updates on Juvenile Systemic Scleroderma

幼年系统性硬皮病(juvenile systemic scleroderma,JSSc)是指16岁以下青少年发生的系统性硬皮病。JSSc与成人系统性硬皮病(systemic scleroderma,SSc)相比有其自身的特点。本文复习相关文献就JSSc的诊断标准、流行病学、病因、发病机制、临床表现、与成人SSc的区别、治疗及预后作一简单的综述,以加强对JSSc的认识,为临床诊断和治疗JSSc提供依据。

Juvenile systemic scleroderma （JSSc） is defined as happened to the young persons below 16 years old. This disease has its own characteristics when compared with the adult systemic scleroderma （SSc）. This article reviews the relevant literatures and describes the diagnostic criteria, epidemiology, cause, pathogenesis,clinical manifestations,the difference frow adult SSe, treatment, and prognosis of JSSc,as well as strengthens the understanding of JSSc, to provide the evidence for clinical diagnosis and treatment of JSSc.