高岭土磁性复合材料表面印迹聚合物选择性吸附分离环丙沙星

Selective Adsorption and Separation of Ciprofloxacin by Molecularly Imprinted Polymers Based on Magnetic Kaolinite Composites

以氨基改性的磁性高岭土为基质材料,利用电子转移产生催化剂的原子转移自由基聚合法制备磁性高岭土表面印迹聚合物(MMIPs)。通过FTIR、TEM、TGA、XRD和VSM等方法对其物理化学性质进行表征,其比表面积112 m2·g-1,且具有较好的热稳定性、超顺磁性(Ms=13.365 emu·g-1)。吸附性能研究表明,准二级动力学模型能较好地描述MMIPs对环丙沙星(CIP)吸附动力学行为,Langmuir等温模型能较好地拟合MMIPs对CIP的吸附平衡数据,25℃时MMIPs的单分子层吸附容量为89.36 mg·g-1。选择性实验研究表明,MMIPs对CIP具有较好地选择识别性。结合高效液相色谱分析技术,MMIPs已成功应用于鲜鱼样品中痕量CIP的分离、富集和回收,CIP的回收率为92.15%。

Based on the magnetic kaolinite-MPS, magnetic molecularly imprinted particles （MMIPs） were further synthesized via activators regenerated by electron transfer atom transfer radical polymerization （AGET ATRP）. The as-prepared MMIPs were charcterized by FTIR, TEM, XRD, TGA and VSM, which indicated that the MMIPs exhibited magnetic sensitivity （Ms=13.365 emu·g-1）, thermal stability and the larger specific surface area（112 m2·g-1）. The results of batch adsorption experiments suggested that pH value of 6.0 in testing solution was the optimal adsorption condition. The kinetic properties of MMIPs were well described by the pseudo-second-order model. The Langmuir isotherm model was fitted to the equilibrium data, and the monolayer adsorption capacity of MMIPs at 25℃ was 89.36 mg·g-1. The selective recognition experiments demonstrated high affinity and selectivity of MMIPs towards ciprofloxacin （CIP） over competitive antibiotics. Combined with high performance liquid chromatographic analysis technology, the prepared MMIPs were successfully applied to extract trace CIP in fish samples, and the recoveries of CIP was 92.15%.