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生物信息学分析mircoRNA在乳腺癌中的调控网络 被引量:2

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摘要 生物信息学是指综合应用信息科学、数学的理论、方法和技术来管理、分析和利用生物分子数据的一门科学。科学地利用生物分子数据及其分析结果,可以大大提高研究和开发的科学性及效率[1]。miRNA(mircoR NA)是一类由内源基因编码的长度为20~24个核苷酸的非编码单链小分子RNA。miRNA能够与靶信使RNAs(mRNAs)3'-端非翻译区(3'-UTR)互补配对,阻碍mRNA翻译或使其稳定性降低而被降解,从而参与到转录后调控[2]。近年许多研究表明,
出处 《中国医药生物技术》 2016年第6期559-562,共4页 Chinese Medicinal Biotechnology
基金 广州市番禺区中心医院青年基金(2014-Q-03 2014-Q-05) 广东省建设中医药强省项目(20141230) 广州市番禺区科技和信息化局项目(2014-Z03-65)
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