糙叶五加中三萜皂苷等次生代谢产物的研究及其化学分类学意义（英文）

Chemotaxonomic Significance of Triterpenoid Saponins and Other Secondary Metabolites from Acanthopanax henryi

基于化学分类学意义的成分研究，采用多种柱层析手段和波谱学方法，从糙叶五加叶中分离鉴定了23种化合物，包括3种黄酮类物质（1-3）、一个有机酸（4）、16种三萜皂苷（5-20）、一个蒽醌（21）、一个甾体皂苷（22）和一个脑苷N（23）。化合物5、6,11、12、14、15、17、19和20为首次从五加属植物中分离得到；化合物8、13和21为首次从五加科中分得。同时基于这些分离所得的次生代谢产物进一步探讨它们在化学分类上的意义。

Phytochemical investigation of the leaves of Acanthopanax henryi led to the isolation of 23 compounds, inclu- ding three flavoooids （ 1-3）, one organic acid （ 4）, sixteen triterpenoid saponins （ 5-20）, one anthraquinone （21）, one steroidal glycoside （22） and one cerebroside （23）. The structures of the isolates were elucidated by spectroscopic methods and comparison with the reported spectral data. All of these compounds except for 1-3,10 and 23 have previously been isolated from A. henryi. Compounds 5,6,11,12,14,15,17,19 and 20 have been reported from the Acanthopanax genus and compounds 8,13,and 21 are new compounds within Araliaeeae. The chemotaxonomie significance of this in- vestigation based on the isolated compounds is summarized.