清晨高血压对脑梗死复发的影响

The influence of morning hypertension on recurrence of cerebral infarction

目的探讨清晨高血压对脑梗死复发的影响。方法急性脑梗死患者118例分为复发组58例和初发组60例。监测清晨血压（6：00~10：00）、24h动态血压情况,并测量颈动脉内膜中层厚度（IMT）和检查斑块情况。结果两组24-h动态血压监测结果无统计学差异（P〉0.05）,但脑梗死复发组清晨血压水平高于初发组（P〈0.05）。复发组IMT大于初发组,不稳定斑块发生率也高于初发组（P〈0.05）。结论清晨高血压可促进颈动脉粥样硬化的进程,加重颈动脉粥样硬化程度,并与脑梗死复发密切相关。有效控制清晨血压对预防脑梗死的复发有着重要的临床意义。

Objective To investigate the influence of hypertension on the recurrence of cerebral infarction.Methods The blood pressure in the morning（6：00-10：00）and 24 hours ambulatory blood pressure were monitored in 118 patients with acute cerebral infarction（ACI）,who were assigned into two groups of A（with recurrent ACI,58cases）and B（with primary attack of ACI,60cases）.The intima-media thickness（IMT）and plaque of the carotid artery were examined as well.Results The difference of 24-hour ambulatory blood pressure was not significant between two groups（P〈0.05）,but the blood pressure in the morning was higher in group A than that in group B（P〈0.05）.Compared to group B,the IMT of the carotid artery and the incidence of unstable plaque were higher in group A（P〈0.05）.Conclusion Morning hypertension can promote the process of carotid artery atherosclerosis and increase the degree of carotid artery atherosclerosis,and is closely associated with the recurrence of cerebral infarction.Effective control of morning hypertension has an important clinical significance in preventing the recurrence of cerebral infarction.