维生素K_2调节骨代谢的生物学研究回顾

A biological study review of the role of vitamin K_2 in regulating on bone metabolism

维生素K(vitamin K,VK)是一类2-甲基-1,4-萘醌衍生物,维生素K2是一种人体必需的天然营养素,主要分布在肾、骨、生殖器及血管壁等组织,维生素K2除参与体内凝血功能外,还与人体的许多生理功能有关,在骨代谢的多个环节中具有重要作用,其调节骨代谢的机制错综复杂。本文回顾性综述了维生素K2对骨代谢调节的生理作用、动物实验及临床试验研究,以及维生素K2在防治骨质疏松中的重要作用。

Vitamin K（vitamin K,VK） is a class of 2-methyl-1,4- naphthoquinone derivative,and vitamin K2 is one kind of essential natural nutrients,mainly distributed in the kidney,bone,blood vessel walls and genital organs. In addition to coagulation functions,vitamin K2 is related to many physiological functions in the body,and it plays an important role in many areas of bone metabolism,with complex regulation mechanisms. In this paper,we retrospective reviewed the physiological role of vitamin K2 on regulating bone metabolism,animal experiments and clinical trials research,and the important role of vitamin K2 in the prevention and treatment of osteoporosis.