脑出血的病例对照研究

A Case-Control Study on the Intracerebral Hemorrhage

目的:探索脑出血的危险因素,为脑出血的临床防治提供参考。方法:采用成组病例对照研究的方法,选择100例脑出血患者作为病例组,选择100例非心脑血管病科室就诊的同期住院患者作为对照组。结果:经单因素非条件Logistic回归分析,脑梗死、心脏病、高血压病、糖尿病、高盐饮食、吸烟史、体重指数、胆固醇、低密度脂蛋白、尿酸、高密度脂蛋白、体育运动与脑出血发生具有相关性(P<0.05);经多因素非条件Logistic回归分析,吸烟史、高血压病、糖尿病、体重指数、高盐饮食、胆固醇、高密度脂蛋白、体育运动是危险因素(P<0.05),其中高密度脂蛋白胆固醇及体育运动是保护因素。结论:常见外在因素对脑出血的发病起重要作用,开展有针对性的脑出血预防工作,进一步推动脑出血的个体化防治工作。

Objective： To explore the risk factors of [CH, to propose a new strategy about the prevention of intraeerebral hemorrhage（ICH）.Method： By the group ease-contral study, 100 cases of cerebral hemorrhage as patient group, 100 cases in not cardio-eerebrovascular department as control group during the same period.Result： Univariate non-conditional Logistic regression analysis showed that 12 factors related to ICH（P〈0.05）, included ischemic stroke, heart disease, hypertension, diabetes, high sait, smoking, body mass index, total cholesterol, low density lipoprotein eholesterol, uric acid, high density lipoprotein cholesterol, physical activity.Multivariate unconditional Logistic regression analysis showed that 8 factors related to ICH（P〈0.05）, included smoking, hypertension, diabetes, body mass index, high salt, total cholesterol, high density lipoprotein cholesterol, physical exercise, the high density lipoprotein cholesterol and physical activity were protective factors.Conclusion： Common environmental factors play an important role in the pathogenesis of cerebral hemorrhage, to carry out the targeted prevention work, to promote the individual prevention and treatment of cerebral hemorrhage.