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长链非编码RNA在心血管系统中的研究进展 被引量:2

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摘要 非编码RNA(ncRNA)指由基因组的序列转录形成,但不具备指导蛋白质合成的一大类RNA。其中,分子大于200 nt的非编码RNA统称为长链非编码RNA(long non-coding RNA,lncRNA)。随着高通量测序的出现,lncRNA成为新的研究热点。目前,在心血管领域,科研人员主要从发育、病理生理、临床疾病诊断等方面进行着lncRNA方面的研究,并取得了一系列的成果。本文将从lncRNA的分类、功能等方面简要介绍lncRNA,同时列举近期心血管领域的重要研究成果来介绍lncRNA在心血管领域研究进展以及潜在的临床运用前景。
作者 马骏 黄岚
出处 《中国循环杂志》 CSCD 北大核心 2016年第12期1248-1250,共3页 Chinese Circulation Journal
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