苗药五藤膏外贴治疗寒湿阻络型膝骨关节炎的临床研究

Clinical Study on Treating Cold Dampness Resistance Winding Type of Knee Osteoarthritis with Miao Medicine Wu Teng Plaster

目的:探讨苗药五藤贴膏治疗寒湿阻络型膝骨关节炎(KOA)的临床疗效。方法:将120例符合寒湿阻络型KOA诊断标准的患者按1:1的比例随机分2组,苗药五藤贴膏治疗组60例(90膝)和巴布膏对照组60例(86膝)。分别予五藤贴膏和巴布膏局部贴敷治疗,2周为1个疗程。治疗结束后评价临床疗效,并采用WOMAC量表和ISOA评分评价关节疼痛及关节功能改善情况。结果:治疗组总有效率为95.0%,对照组总有效率为90.0%,2组总有效率比较无统计学差异(P>0.05)。2组治疗后WOMAC量表和ISOA关节炎评分均较治疗前改善(P<0.01或P<0.05)。苗药五藤贴膏治疗组WOMAC关节VAS评分和ISOA关节疼痛改善均优于巴布膏对照组(P<0.05),但关节功能障碍评分2组比较无统计学差异(P>0.05)。结论:苗药五藤贴膏能够提高寒湿阻络型KOA患者的临床疗效,能够明显改善患者关节疼痛。

Objective：To investigate the clinical treatment effect treating knee osteoarthritis （KOA） with cold dampness syndrome. dampness syndrome according to the ratio of 1：1 were randomly and of the Miao medicine Wu Teng plaster on Method： 120 patients of KOA with cold evenly divided into 2 groups： Miao medicine Wu Teng plaster treatment group （90 knees） and Flurbiprofen Cataplasms control group （86 knees）. 2 groups of patients were treated with Wu Teng plaster and Flurbiprofen Cataplasms respectively for 2 weeks. After the treatment, the clinical efficacy was evaluated, and the WOMAC scale and ISOA score were used to evaluate the improvement of joint pain and joint function. Results ： The total effective rate of treatment group was 95 %, and the total effective rate of the control group was 90%. There was no significant difference in the total effective rate between the 2 groups （P 〉 0.05 ）. The scores of WOMAC scale and ISOA arthritis were improved after treatment in 2 groups （P 〈 0. 01 or P 〈 0.05）. Both of WOMAC VAS score and ISOA joint pain of Miao medicine Wu Teng plaster treatment group were better than those of Flurbiprofen Cataplasms control group （P 〈 0.05 ）, but the joint function score of 2 groups had no significant difference. Conclusion： Miao medicine Wu Teng plaster can improve the clinical efficacy in patients with the syndrome of cold dampness KOA, and can sig- nificantly relieve joint pain of patients.