摘要
目的了解病毒对南通市感染性腹泻的影响及其流行规律,为制定病毒性腹泻防治措施提供基础资料。方法采集哨点医院感染性腹泻患者的粪便标本,运用RT-PCR或PCR技术检测诺如病毒、轮状病毒、星状病毒、札如病毒和腺病毒核酸,利用Excel 2007及SPSS 19.0对资料进行统计和流行病学分析。结果 987份感染性腹泻样品中病毒核酸阳性样品为96份,总阳性率为9.73%,诺如病毒2型的阳性率最高,为5.27%;其次为轮状病毒和星状病毒,分别为2.43%、1.14%;札如病毒、腺病毒和诺如病毒1型检测阳性率较低,分别为0.61%、0.41%和0.30%;混合感染的感染率为0.41%。病毒核酸阳性以诺如病毒2型和轮状病毒为主,分别占阳性总数的52.00%、24.00%。轮状病毒与诺如病毒感染出现的高峰皆为冬春季。结论病毒是南通市感染性腹泻的重要因素之一,诺如病毒和轮状病毒是该地区病毒性腹泻的主要病原,流行季节以冬春季为主。
[Objective] To explore influences of causative viruses on infectious diarrhea in Nantong City,analyze the epidemiological features,and provide the basis for developing the prevention and control measures.[Methods]Feces samples were collected from patients with infectious diarrhea in sentinel hospitals,and real-time PCR or PCR technologies were used to detect specific RNA of Norovirus,Rotavirus,Astrovirus,Sappovirus and Adenovirus.Excel 2007 and SPSS 19.0 were applied in the epidemiological analysis.[Results]There were 96 positive cases for virus RNA among 987 samples,with a total positive rate of 9.73%.NorovirusⅡ had the highest positive rate(5.27%),followed by Rotavirus(2.43%) and Astrovirus(1.14%),while the positive rates of Sappovirus,Adenovirus and Norovirus Ⅰ were lower relatively,which was 0.61%,0.41% and 0.30%,respectively.The mixed infection rate was 0.41%.Norovirus Ⅱ and Rotavirus were the prevalent pathogens for viral diarrheal cases,respectively accounting for 52.00% and 24.00% in positive samples.The infection peaks of Norovirus and Rotavirus appeared in winter and spring.[Conclusion]Causative viruses are important pathogens of infectious diarrhea in Nantong City.Norovirus and Rotavirus are the prevalent pathogens for viral diarrheal,while winter and spring are predominant epidemic seasons.
出处
《职业与健康》
CAS
2016年第22期3080-3082,3087,共4页
Occupation and Health
基金
南通市科技局2010K应用研究领域科技项目(K2010027)