门诊处方抗菌药物合理应用的调查研究

Investigation of rational application of antibacterial agents in outpatient prescription

目的研究调查门诊处方抗菌药物合理应用情况,为宏观管理与合理应用抗菌药物提供重要参考依据。方法回顾性分析门诊处方1500张,探究各类抗菌药物的使用情况、联用与单用处方数和比例以及使用种类等。结果 1500张门(急)诊处方中,450张为抗菌药物处方(抗菌药物使用513次),占总处方数的30%;应用次数最多为头孢菌素类,应用341次,占66.47%;其次为大环内酯类药物,应用80次,占15.59%;排列第三的是氟喹诺酮类药物,应用38次,占7.41%。结论用药无指征、联用不合理与选药不合理等均为不合用应用抗菌药物的主要表现,医护人员应当对抗菌药物的监管使用工作予以进一步加强,有效确保临床用药的规范性。

Objective To research rational application of antibacterial agents in outpatient prescription, and to provide important reference for macro management and rational application of antibacterial agents. Methods A retrospective analysis was made on 1500 outpatient prescriptions to investigate applied antibacterial agents, combined and single application, proportion and types. Results Among 1500 outpatient （emergency） prescriptions, there were 450 prescriptions with antibacterial agents （applied for 513 times）, accounting for 30%. Cephalosporins was the most frequently applied agent for 341 times, accouniing for 66.47%, followed by macrolides for 80 times, accounting for 15.59%, and fluoroquinolones for 38 times, accounting for 7.41%. Conclusion Main manifestations of irrational application of antibacterial agents include non indication, irrational combination and selection. Therefore, enhancement of supervision and application of antibacterial agents by medical staff can effectively ensure standardization of clinical medication.