2015镇江市流感病原学监测结果分析

Analysis of pathogenic surveillance results for influenza in 2015 in Zhenjiang

目的分析镇江市2015年流感病毒流行情况,为今后科学有效地防控流感提供依据。方法收集2015年镇江市国家级流感哨点监测医院流感样病例(ILI)标本3 237份,利用实时荧光定量PCR法进行病毒核酸检测,并对ILI报告数据、病原学监测数据进行分析。结果 3 237份咽拭子标本共检出流感病毒核酸阳性464份,总阳性率为14.33%,其中甲型H1N1流感病毒3份、季节性H3N2型流感病毒164份、BY型流感病毒297份。男性和女性阳性率分别为14.10%和14.55%,不同性别阳性率比较,差异无统计学意义(χ2=0.13,P>0.05)。流感全年出现,冬季和夏季2个小流行高峰。1月-3月优势流感毒株为BY型,7月-9月优势流感毒株为季节性H3N2型。结论 2015年镇江市共出现3种毒株流行。应进一步加强流感哨点监测工作,加强人员密集场所的暴发性疫情监测,警惕新型流感病毒株的出现和流行。

Objective To analyze the epidemic situation of influenza virus in Zhenjiang in 2015,so as to provide basis for the scientific and effective control of influenza. Methods 3 237 influenza-like illness（ ILI） samples were collected in national influenza surveillance hospitals in Zhenjiang in 2015. Influenza virus nucleic acid was detected using real-time fluorescent polymerase chain reaction. Reported data of influenza-like illness（ ILI） and pathogen surveillance results were analyzed.Results 464 cases were influenza virus positive,with total positive rate of 14. 33%,including 3 strains of H1N1 subtype,164 strains of H3N2 subtype and 297 strains of BY subtype. The positive rates of male and female were 14. 10% and 14. 55%,respectively. There was no statistical significance on the difference（ χ2= 0. 13,P 0. 05）. Annual two small epidemic peaks appeared in winter and summer. The dominant subtype was BY during January-March. However,the dominant virus subtype was H3N2 during July-September. Conclusion 3 virus strains had been epidemic in Zhenjiang in 2015. We should further strengthen the monitoring work in influenza monitor sentinel hospitals,enhance the surveillance of influenza outbreaks in personnel intensive areas,and pay more attention to the occurrence and epidemic of new influenza virus.