摘要
One novel spiro-compound(C_(26)H_(21)NO_3) has been synthesized and characterized by means of NMR spectroscopy,elemental analyses and X-ray diffraction. The single crystal belongs to the monoclinic system,space group P21/c with a = 8.8039(7),b = 24.123(2),c = 10.0751(9) ?,β = 108.403(3)°,M3r = 395.44,V = 2030.3(3) ?~3,Z = 4,D_c = 1.294 g/cm,F(000) = 832.0,μ = 0.085 mm^(-1),R = 0.0801 and wR = 0.2228. The title compound shows good activities against Micrococcus tetragenus,Bacillus cereus,Bacillus subtilis,Staphylococcus aureus,S.albus and Escherichia coli.
One novel spiro-compound(C_(26)H_(21)NO_3) has been synthesized and characterized by means of NMR spectroscopy,elemental analyses and X-ray diffraction. The single crystal belongs to the monoclinic system,space group P21/c with a = 8.8039(7),b = 24.123(2),c = 10.0751(9) ?,β = 108.403(3)°,M3r = 395.44,V = 2030.3(3) ?~3,Z = 4,D_c = 1.294 g/cm,F(000) = 832.0,μ = 0.085 mm^(-1),R = 0.0801 and wR = 0.2228. The title compound shows good activities against Micrococcus tetragenus,Bacillus cereus,Bacillus subtilis,Staphylococcus aureus,S.albus and Escherichia coli.
基金
Project supported by the Natural Science Foundation of Hainan Province(No.20162033)
the Cultivation Research Foundation of Hainan Medical University(HY2015-02)