2-咪唑啉衍生物的合成方法

Synthesis of the Derivative of Oxazoline

介绍了一种用不同的脒化合物合成2-咪唑啉衍生物的方法。对反应催化剂的种类进行了筛选,对催化剂用量、反应温度、溶剂和反应时间进行了优化,结果表明,不同的2-咪唑啉衍生物的产率均达到80%以上。该方法操作简单、安全、产率高且条件温和。

The article describes a method for the synthesis of the derivative of 2-imidazolines using different amidine. This method has several advantages over previous methods：operational simplicity, safety, high yield and mild conditions. In this paper, the reaction of the kinds of catalyst, temperature, solvent, time is optimized. Finally, the yield of derivative of oxazoline is reached 80%.