齐拉西酮治疗精神分裂症的疗效及TC、TG、LDL-C、Lep水平变化分析

Analysis of the efficacy of the treatment of schizophrenia by Ziprasidone capsule and TC,TG LDL-C,change,Lep levels in patients

目的探讨齐拉西酮胶囊对精神分裂症的治疗效果及胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白(LDL-C)、瘦素(Lep)的水平变化。方法择取100例精神分裂症的患者,随机分为研究组和对照组,研究组患者采用齐拉西酮胶囊治疗,对照组患者采用利培酮进行治疗。所有患者在治疗前后进行PANSS评分并比较两组患者的疗效,同时检测上述患者的TC、TG、LDL-C、Lep水平。结果治疗后研究组患者的PANSS总分要明显低于对照组;研究组患者的总体有效率较对照组高;治疗后对照组患者的各项代谢指标均有明显变化;研究组不良反应低于对照组,P<0.05。结论齐拉西酮对精神分裂症具有较好的疗效。

Objective Discussion of ziprasidone capsule in the treatment of schizophrenia. Method Will pick of the 100 cases of schizophrenia patients, randomly divided into 2 groups, the treatment group were treated by ziprasidone capsule, the control group patients treated with risperidone. Compare the curative effect of two groups of patients, TC, TG, LDL - C, Lep level. Results Group after treatment in patients with PANSS scores significantly lower than the control group; The team overall efficient than control group in patients with high; The control group after treatment in patients with various metabolic indexes have obvious change; The team adverse reaction is lower than the control group, P〈 0.05. Conclusion Ziprasidone for schizophrenia has good curative effect.