藏红花药物高能超声提取的工艺参数优化

Optimization of Tech-Parameters for Medicine Extraction in Crocus Sativus L. based on HIU

高能超声空化效应运用于中药成分提取的关键问题是工艺设计的科学性。为揭示超声空化效应的作用机制,探索藏红花超声提取工艺的最佳化,采取理论分析和实验验证,对高能超声提取中药的作用机制进行了研究,并基于藏红花提取物药用成分的HPLC检测数据,实现超声提取工艺的参数优化。研究结果表明,超声空化效应的能量特征及其作用机制是可控的。另外,依据提取物中主要成分（Crocus-I和Crocus-II）含量最大化原则,得知藏红花超声提取工艺的最佳参数为：功率密度为2.0～3.0 W/cm^3;提取时间为20～30 min。

The key problem for Chinese medicine based on HI ultrasonic cavitation is the technique scientificalnes. For understanding the reaction mechanism of ultrasonic cavitation and the technical optimization of extracting Crocus sativus L based on the content of medicine composition in extraction. The mechanism of ultrasonic extraction through the theory and experiment are used for obtaining the technique optimization according to the data of HPLC detection. The conclusions are that the characters of ultrasonic energy could be controlled and the best technical characters are. The power density is 2.0-3.0 W / cm^3 and the extracting time is 20-30 min according to the content maximization.