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中医辩证治疗重症肺炎并发抗生素相关性腹泻的疗效观察 被引量:19

Clinical observation of chinese medicine dialectic on treatment of severe pneumonia patients complicated antibiotic-associated diarrhea
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摘要 目的通过对重症肺炎并发抗生素相关性腹泻(antibiotic-associated diarrhea,AAD)的患者进行中医辩证施治,观察中医治疗AAD的临床疗效,从而评价中医辩证治疗在重症肺炎并抗生素相关性腹泻中的价值和意义。方法采用随机对照方法,将40例重症肺炎合并AAD的患者分为治疗组和对照组各20例,治疗组采用中医辩证,分为脾肾阳虚和湿邪内阻两证型,分别给予口服中药加味胃关煎和加味人参败毒散治疗5天。对照组采用西药常规治疗,给予口服甲硝唑+金双岐治疗5天。比较两组之间各项指标的差异性。结果治疗组和对照组在临床症状评分改善、药物起效时间、症状复发率、住院时间和住院费用方面的比较,差异有统计学意义(P<0.05);两组治疗前后血常规、肝功能、肾功能的变化比较,差异无统计学意义(P>0.05)。结论中医辩证治疗重症肺炎合并抗生素相关性腹泻,在临床疗效、卫生经济学方面,要优于传统的西医治疗方案,且安全性好,病人依从性高,可在临床推广应用。 Objective To evaluate the value and significance of Chinese medicine dialectic treatment of severe pneu- monia patients complicated antibiotic-associated diarrhea (AAD). Methods 40 severe pneumonia patients with AAD were divided into treatment group and control group. 20 cases in treatment group were divided into Pishen Yangxu group and Shixie Neizhu Group according Chinese medicine dialectic. Pishen Yangxu group and Shixie Neizhu Group were treated with Jiaweiweiguanjian and Jiaweirenshenbaidusan for 5 days. 20 cases in control were treated with conventional treatment. All cases were treated with oral metronidazole and bifidobacterium lactobacillus for 5 days. The related indexes were observed. Results The differences of improvement of clinical symptom scores, drug onset time, symptoms recurrence rate, length and cost of hospitalization were statistically significant between treatment group and control group (P〈0.05). The differences of blood routine, liver and kidney function between treatment group and control group were not statistically significant (P〉0. 05). Conclusion The clinical curative effect and health economics of Chinese medicine dialectical treatment of severe pneumonia patients complicated AAD is better than that of conventional treatment.
出处 《西部医学》 2017年第1期89-92,96,共5页 Medical Journal of West China
基金 攀枝花市科技局科研课题(2014CY-S-19-5-5)
关键词 中医治疗 重症肺炎 抗生素相关性腹泻 临床疗效 Chinese medicine treatment Severe pneumonia Antibiotic-associated diarrheal Clinical curative effect
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