期刊文献+

疏风解毒胶囊对慢性阻塞性肺疾病急性加重期的疗效评价 被引量:23

Curative effect evaluation of Shufeng Jiedu Capsules for the treatment of acute exacerbation of chronic obstructive pulmonary disease
原文传递
导出
摘要 目的:评价疏风解毒胶囊对慢性阻塞性肺疾病(COPD)急性加重期的临床疗效和安全性。方法:COPD急性加重期患者40例按完全随机分组法分为:试验组20例,对照组20例。试验组疏风解毒胶囊口服加常规治疗,对照组常规治疗,疗程1周。比较两组患者临床症状缓解情况、住院天数、血常规及超敏C-反应蛋白(hsCRP),并取住院时、出院时患者血清行呼吸道合胞病毒Ig M、甲型流感病毒抗原检测。结果:治疗后,试验组临床显效率高于对照组(P<0.01);试验组住院天数明显少于对照组(P<0.01)。治疗前两组患者白细胞计数(WBC)、中性粒细胞百分比(N%)、hs-CRP、血清呼吸道合胞病毒Ig M、甲型流感病毒抗原等临床指标比较差异无统计学意义。治疗后两组患者WBC、N%、hs-CRP、甲型流感病毒抗原等临床指标较治疗前均显著降低(P<0.01),血清呼吸道合胞病毒Ig M比较,差异无统计学意义,其中,试验组患者血清WBC、N%、hs-CRP、甲型流感病毒抗原等临床指标好于对照组(P<0.01)。试验组出现轻微恶心1例。结论:疏风解毒胶囊对COPD急性加重期患者疗效确切安全,可减少住院时间。 Objective:To evaluate the curative effect and safty of Shufeng Jiedu Capsules for the treatment of acute exacerbation of chronic obstructive pulmonary diseases(AECOPD).Methods:Forty patients with AECOPD were randomly divided into experimental group and control group,twenty patients each group.The experimental group was treated with conventional therapy and Shufeng Jiedu Capsules,the control group with conventional therapy.The course of treatment was 1week.The changes of clinical symptoms and signs,content hypersensitive C-reactive protein(hs-CRP),blood routine examination,IgM of respiratory syncytial virus and antigen of influenza A virus in serum were observed pretherapy and post-treatment,recored the hospital stays every patients.Results:The experimental group had a better effect than control group(P〈0.01),and had less hospital stays than control group(P0.01).The clinical level of WBC,N%,hs-CRP and antigen of influenza A virus of two groups after treatment were lower than those of two groups before treatment(P0.01),and the clinical level of WBC,N%,hs-CRP and antigen of influenza A virus of the experimental group were lower than those of control group after treatment(P0.01),IgM of respiratory syncytial virus without significant difference between tow groups.Conclusion:The patients with AECOPD can benefit from Shufeng Jiedu Capsules,and the hospital stays can be shortened by treatment in Shufeng Jiedu Capsules.
出处 《中华中医药杂志》 CAS CSCD 北大核心 2017年第1期347-350,共4页 China Journal of Traditional Chinese Medicine and Pharmacy
关键词 疏风解毒胶囊 慢性阻塞性肺疾病 急性加重期 临床观察 Shufeng Jiedu Capsules Acute exacerbation Chronic obstructive pulmonary diseases(COPD) Clinical observation
  • 相关文献

参考文献10

二级参考文献74

共引文献1505

同被引文献259

引证文献23

二级引证文献156

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部