康复期精神分裂症与双相情感障碍患者认知功能损害程度对比分析

Comparative analysis of cognitive impairment in patients with schizophrenia and bipolar disorder in rehabilitation period

目的比较分析康复期精神分裂症与双相情感障碍患者认知功能损害程度,为临床症状提供参考。方法选取住院治疗的康复期精神分裂症和双相情感障碍患者各50例,采用数字符号、视觉再生、数字广度、连线测试、韦氏康星卡片分类测试(WCST)等对患者认知功能进行评估,利用x^2与t值对数据加以检验。结果双相障碍组在数字符号(37.31±12.83)、视觉再生倒背评分(7.58±3.05)大于精神分裂症组,WCST中分类个数(4.12±2.04)大于精神分裂症组,WCST中错误数(15.88±7.85)及持续错误数(8.67±3.49)少于精神分裂症组,比较差异有统计学意义(P<0.05)。结论康复期的双相情感障碍和精神分裂症患者仍然存在认知功能损害,双相情感障碍患者认知功能损害程度相对于精神分裂症患者轻。

Objective To compare and analyze the degree of cognitive impairment in patients with schizophrenia and bipolar disorder, and provide reference for clinical symptoms. Methods The inpatient treatment of schizophrenia and bipolar disorder in patients with 50 cases, the digit symbol, digit span, visual reproduction, connection test, Wisconsin Card Sorting Test Satellite （WC- ST） to evaluate the cognitive function of patients. Use x2test and t value to the data .Results Bipolar disorder group in the number of symbols （37.31 ± 12.83 ）, visual reproduction Daobei score （ 7.58±3.05 ） greater than the schizophrenia group, WCST classification number （4.12±2.04 ） is greater than the schizophrenia group, number of errors （ 15.88±7.85 ） and continuous error （ 8.67±3.49 ） in the WCST number is less than the schizophrenia group, the difference was statistically significant （P〈0.05）.Conclusion Patients with bipolar disorder and schizophrenia still have cognitive impairment, and the degree of cognitive impairment in patients with bipolar disorder is less than that of schizophrenia patients.