腹腔镜肝癌切除术的临床疗效及对免疫功能影响的研究

Effects of laparoscopic hepatectomy on postoperative rehabilitation and immune

目的:探讨腹腔镜下肝癌切除术的临床疗效及对机体免疫功能的影响。方法:80例原发性肝癌患者根据手术方式分成开腹组(44例)和腹腔镜组(36例)。比较两组手术时间、术中出血量、术后排气时间、住院时间、住院费用及手术前后肝功能、外周血Th17细胞百分比。结果:腹腔镜组手术时间、术中出血量、术后排气时间、术后住院时间均少于开腹组(P<0.05)。两组住院费用比较差异无统计学意义(P>0.05)。两组术前和术后第2天肝功能比较差异无统计学意义(P>0.05);术后第10天腹腔镜组肝功能改善优于开腹组(P<0.05)。术前两组外周血Th17百分比相近,术后1个月腹腔镜组Th17百分比较开腹组明显降低(P<0.05)。结论:腹腔镜下肝癌切除术手术时间短,术中出血少,对机体免疫系统影响小,更利于恢复。

Objective： Discuss the effect on body of Laparoscopic liver resection. Methods： Methods： 80 cases of primary liver cancer patients according to the operation method is divided into laparotomy group（44 cases）and laparoscopic group（36 cases）. Compare two groups of operation time,intraoperative blood loss, postoperative exhaust time, length of hospital stay, hospital expenses and liver function before and after surgery, peripheral blood Th17 cell percentage. Results： the laparoscopic group operation time, intraoperative blood loss, postoperative exhaust time, postoperative hospital stay were less than laparotomy group （P〈0.05）. The hospitalization cost more similar between the two groups has no statistical significance （P〉0.05）. The preoperative and postoperative liver function 2 days is similar between the two groups had no statistical significance （P〉0.05）; The lOth day after laparoscopic liver function improved better than laparotomy group （P〈0.05）. Two groups of preoperative peripheral blood Th17 percentage, 1 month after laparoscopic group Th17 percentage is laparotomy group significantly decreased（P〈0.05）. Conclusion： The effect on the body＇s immune system of laparoscopic resection of liver cancer is smaller, more conducive to recover.