我院2011-2014年35665例呼吸道感染患儿肺炎支原体抗体检测结果分析

Mycoplasma Pneumoniae Antibody Testing Results Analysis of 35,665 Children with Respiratory Tract Infection in Our Hospital,2011-2014

目的:探讨呼吸道感染患儿肺炎支原体(MP)感染的规律与特点。方法:选取我院2011-2014年收治的呼吸道感染患儿35 665例,检测血清MP抗体,采用回顾性研究方法分析MP抗体阳性率在不同性别、年龄、季节、病种间的差异,并随访观察患儿MP抗体的转阴时间。结果:呼吸道感染患儿血清MP抗体总体阳性率为14.6%,其中呼吸道感染患儿血清MP抗体阳性率性别比较差异有统计学意义,女性(17.4%)高于男性(12.4%,P<0.01);年龄比较差异有统计学意义(P<0.01),以7~9岁组最高(23.9%);季节比较差异有统计学意义(P<0.01),以冬季(12月至次年2月)最高(17.1%),夏季(6-8月)最低(10.8%);病种比较差异有统计学意义(P<0.01),以大叶性肺炎最高(72.0%),急性上呼吸道感染最低(7.0%)。患儿MP抗体转阴时间集中在首次检测确诊后3~9个月。结论:MP是儿童呼吸道感染主要病原之一,呼吸道感染患儿血清MP抗体总体阳性率为14.6%,女性高于男性;MP感染多见于大叶性肺炎,以7~9岁组患儿多见,冬季高发;MP感染患儿MP抗体转阴时间集中在首次检测确诊后3~9个月。

Objective： To explore the characteristics and laws of Mycoplasma pneumoniae（ MP） infection. Methods： MP antibodies were detected in 35,665 children with respiratory infection from 2011 to 2014,and the collected data were analyzed by the method of retrospective control study. Results： Among the 35,665 samples,the positive rate was 14. 6%. The positive rate of male was 12. 4%while the female was 17. 4%,there was a significant difference among the gender（ P〈0. 01）. There was a significant difference in the infection rate of different age groups（ P〈0. 01）. The positive rate of 7 to 9 years old children accounted for 23. 9% that was higher than the others. MP infection occurred in the whole year. The positive rates of winter were higher than the other seasons. There was a significant difference in the diseases（ P〈0. 01）. The proportion of lobar pneumonia was highest,accounted for 72. 0%,acute upper respiratory tract infection was lowest,accounted for 7. 0%. The average time of positive MP antibody reversing to negative were 3 to 9months. Conclusion： Among respiratory infections,MP infection is the major cause for children especially 7 to 9 years old. It occurs more in female and often occur in winter. The average time of positive MP antibody reversing to negative are 3 to 9 months.