急性一氧化碳中毒迟发性脑病的诊疗进展

Therapeutic and diagnostic progress of delayed encephalopathy caused by acute carbon monoxide poisoning

急性一氧化碳中毒是我国北方冬季的常见病,其致死率和致残率高。急性一氧化碳中毒以后会导致患者心血管系统和中枢神经系统损害为主的多脏器损伤,通过临床综合有效的治疗,大部分患者可以痊愈,但是重度一氧化碳中毒患者假愈期后易出现迟发性脑病,其发病率大概为10%~30%。目前发病机制尚不是很清楚,综合其相关危险因素,早期预测及恰当的诊疗迟发性脑病是临床工作中急需解决的难题。本文对急性一氧化碳中毒迟发性脑病的发病机制、相关危险因素及诊疗进行阐述。

Acute carbon monoxide poisoning is a common disease in the north of China, and the mortality rate and disability rate are very high. Acute carbon monoxide poisoning can lead to multiple organ damage in cardiovascular system and central nervous system damage in patients. Although most patients can be cured by clinical comprehensive effective treatment, but severe carbon monoxide poisoning patients prone to delayed encephalopathy after the false, its incidence is about 10%-30%. The pathogenisis is not elucidated well, but comprehensive risk factors, early prediction and proper diagnosis and treatment of delayed encephalopathy is a difficult problem to be solved in clinical work. The pathogenesis, risk factors, diagnosis and treatment of delayed encephalopathy after acute carbon monoxide poisoning were described in this paper.