灵芝养肝丸联合肝病治疗仪、拉米夫定治疗小儿慢性乙型肝炎肝纤维化的临床护理

Clinical Nursing of Ganoderma Yanggan Pill Combined with Lamivudine in the Treatment of Pediatric Chronic Hepatitis B Hepatic Fibrosis

目的:探讨灵芝养肝丸联合肝病治疗仪拉米夫定治疗小儿慢性乙型肝炎肝纤维化过程中的有效护理措施。方法:选取2014年1月-2015年1月本院收治的慢性乙型肝炎肝纤维化患儿90例,将其随机分为观察组和对照组各45例,对照组进行常规护理,观察组患儿采取综合性护理措施,比较两组患儿的护理效果。结果:观察组患儿的护理满意率为93.3%(42/45),明显高于对照组;且其不良反应率为2.2%,远低于对照组水平,两组比较差异有统计学意义(P<0.05)。护理后,两组患者症候总分、ALT、AST、DNA数量显著低于对照组,比较差异有统计学意义(P<0.05),观察组护理后SDS得分(41.2±3.8)分,SAS得分(37.2±7.3)分,观察组护理后SDS得分和SAS得分低于对照组,两组比较差异有统计学意义(P<0.05)。观察组中有1例患儿出现持续性高热,不良反应发生率为2.2%;对照组中有3例出现持续性高热,有2例皮肤出现轻度红肿,1例患儿表现出轻度胃肠道反应,不良反应率13.3%,两组比较差异有统计学意义(P<0.05)。结论:在使用灵芝养肝丸联合肝病治疗仪、拉米夫定治疗慢性乙型肝炎肝纤维化患儿时,应根据治疗步骤采取对应的综合性护理措施,进一步改善治疗效果及预后质量。

Objective：To investigate the Ganoderma Yanggan pill combined with liver disease therapy instrument of lamivudine in the treatment of children with chronic hepatitis B and hepatic fibrosis in the effective nursing measures.Method：A total of 90 children with chronic hepatitis hepatitis and hepatic fibrosis in our hospital were selected from 2014 January to 2015 January,they were randomly divided into observation group and control group,45 cases in each group.The control group was given routine nursing,observation group was taken the comprehensive nursing measures,the nursing effects of two groups were compared.Result：The nursing satisfaction rate in observation group was 93.3%（42/45）,significantly higher than the control group of 2.2%,the difference was statistically significant（P〈0.05）.After nursing,the symptoms score, ALT, AST and DNA number of observation group were significantly lower than the control group,the difference was significant（P〈0.05）. After nursing,The observation group SDS was （41.2±3.8） score, SAS was（37.2±7.3） score,lower than the control group,the differences were statistically significant（P〈0.05）.Observation group had 1 case occurred in children with persistent high fever, adverse reactions occurred rate was 2.2%;control group with 3 cases of persistent high fever,2 cases of skin had mild redness and swelling,1 cases showed mild gastrointestinal reactions, adverse reaction rate was 13.3%,the differences were statistically significant（P〈0.05）.Conclusion：In treatment of chronic hepatitis B hepatic fibrosis patients with childhood using Ganoderma Yanggan pill combined liver disease therapy instrument,lamivudine should be treated according to the steps to take corresponding comprehensive nursing measures,to further improve the therapeutic effect and the prognosis and quality of life.