清热利湿泄毒化瘀法治疗急性迁延型痛风临床观察

Clinical observation on treating acute prolonged gout by the Qingre Lishi Xiedu Huayu therapy

目的:研究清热利湿泄毒化瘀法治疗急性迁延型痛风的临床效果。方法:选取我院近2年收治的83例急性迁延型痛风患者,按照随机数字表法将其分为西医疗法组和中医疗法组。西医疗法组以西医药物治疗;中医疗法组以清热利湿泄毒化瘀法治疗。观察指标为痛风控制率、副反应率以及治疗后患者关节症状积分、血尿酸、血沉。结果:中医疗法组相比于西医疗法组痛风控制率更高,x2检验统计学差异显著,P<0.05;中医疗法组相比于西医疗法组副反应率更低,x2检验统计学差异显著,P<0.05;治疗前两组关节症状积分、血尿酸、血沉相似,t检验统计学差异不显著,P>0.05;治疗后中医疗法组相比于西医疗法组关节症状积分、血尿酸、血沉改善更显著,t检验显示差异显著,P<0.05。结论:清热利湿泄毒化瘀法治疗急性迁延型痛风临床效果确切,可有效改善患者关节症状、血沉和血尿酸水平,安全有效,值得推广。

Objective： To study the clinical effect of the Qingre Lishi Xiedu Huayu therapy on acute persistent gout. Methods： 83 patient were divided into two groups. The TCM group took the Qingre Lishi Xiedu Huayu therapy. Results： In the TCM therapy group, the controlling rate was higher （P〈0.05）; and side effects were less （P〈0.05）. There was no significant difference between two groups in the symptom score, serum uric acid and erythrocyte sedimentation rate before treatment （P〉0.05）. After the treatment, there were significant differences in joint symptom score, serum uric acid, and improvement of erythrocyte sedimentation in the TCM group, P〈0.05. Conclusion： The Qingre Lishi Xiedu Huayu therapy is effective, by improving joint symptoms, ESR and serum uric acid level, with safety, worthy of promotion.