健脾渗湿消肿方配合小剂量强的松和止血中药治疗IgA肾病疗效观察

Observation on treating IgA nephropathy with the Jianpi Shenshi Xiaozhong prescription, prednisone of small dose plus hemostasis of TCM medicine

目的:观察健脾渗湿消肿方治疗Ig A肾病的疗效。方法:将经肾活检证实为Ig A肾病的患者随机分为治疗组和对照组,各30例,同时观察两组患者临床症状、体征、尿红细胞、蛋白尿及免疫球蛋白等指标。结果:治疗组完全缓解率和总有效率分别为40.0%、93.3%,对照组完全缓解率和总有效率分别为20.0%、53.3%,治疗组疗效优于对照组(P<0.01)。治疗组尿红细胞、蛋白尿改善明显优于对照组(P<0.01,P<0.05)。结论:健脾渗湿消肿方联合西药治疗Ig A肾病,有显著的疗效,对Ig A肾病的血尿及蛋白尿有明显的治疗作用。

Objective： To observe effects of the Jianpi Shenshi Xiaozhong prescription on IgA nephropathy. Methods： Patients with IgA nephropathy were randomly divided into the treatment group and control group, 30 cases in each. The clinical symptoms, signs, urinary red blood cells, proteinuria and immune globulin were observed. Results： The complete remission rate and total efficiency were 40.0% and 93.3% in the treatment group respectively, and better than 20.0% and 53.3% in the control group （P〈0.01）. The improvement of urinary red blood cells and proteinuria was significantly better in the treatment group （P〈0.01, P〈0.05）. Conclusion： The Jianpi Shenshi Xiaozhong prescription shows a significant effect on IgA nephropathy hematuria and proteinuria.