血府逐瘀汤治疗颅脑外伤所致睡眠障碍的临床研究

Clinical observation on treating mental disorders due to brain damage with the Xuefu Zhuyu decoction

目的:观察血府逐瘀汤治疗颅脑外伤引起睡眠障碍的效果。方法:采用前瞻性随机对照研究,将泰州市中医院重症医学科2008—2014年内收治的121例颅脑外伤引起的睡眠障碍患者,随机分为西医组和中医组,两组均执行脑外伤基础性治疗,中医组(61例)加用中药血府逐瘀汤煎服,西医组(60例)加用氯硝安定或思诺思治疗。比较两组治疗前后获益及匹茨堡睡眠(PSQI)评分的大小。结果:中医组在睡眠质量、促进神经功能恢复等方面明显优越于西医组;PSQI评分中医组明显低于西医组,差异有统计学意义(P<0.05);中医组总有效率明显高于西医组,两者差异有统计学意义(P<0.05)。结论:血府逐瘀汤能有效治疗脑外伤引起的睡眠障碍。

Objective： To observe effects of the Xuefu Zhuyu decoction on treating mental disorders due to brain damage. Methods： Using prospective randomized controlled study, 121 patients with mental disorders due to brain damage of Taizhou Chinese hospital from 2008-2014 were randomly divided into the western medicine and the traditional Chinese medicine group, The two groups were given the basic treatment of traumatic brain injury, the traditional Chinese medicine group （61 cases） plus the Xuefu Zhuyu decoction and the western medicine group （60 cases） plus clonazepam or Stilnox.Comparing the two groups before and after treatment benefit and the size of the Pittsburgh sleep （PSQI） score.Results： The traditional Chinese medicine group in the aspect sleep quality, Promote the recovery of neural function aspect obviously superior to western medicine group; PSQI score of traditional Chinese medicine group obviously lower than western medicine group, the difference was statistically significant （P 〈 0.05）; The total effective rate in traditional Chinese medicine group was higher; the difference was statistically significant（P 〈 0.05）.Conclusion： The Xuefu Zhuyu decoction can shows good effects on mental disorders due to brain damage.