加减消风散治疗慢性荨麻疹的临床研究

Clinical research of modified Xiaofeng powder in treating chronic urticaria

目的:研究临床上采用加减消风散的疗法治疗慢性荨麻疹的效果。方法:选取从2014年2月—2016年5月在我院就诊的106例荨麻疹患者资料,将其划分成两组,对照组和试验组各53例,对照组采用盐酸西替利嗪片治疗,试验组进行加减消风散治疗,试验过程中观察并记录患者接受治疗后的反应,将两组患者的风团大小、数目、维持存在的时间、皮肤瘙痒程度,复发情况和用药的不良反应发生率做对比。结果:分析试验结果,不难看出疗程结束后,两组患者的风团维持存在的时间、大小及皮肤瘙痒等症状都有所减轻,且行消风散加减法治疗的试验组患者症状的减轻程度在0.05的水平上显著比行盐酸西替利嗪片常规治疗的对照组理想;两组患者治疗后的复发情况及药物不良反应情况方面也有显著差异(P<0.05)。结论:与以盐酸西替利嗪片为代表的传统西药治疗荨麻疹相比,采用加减消风散治疗慢性荨麻疹在临床上有更好的疗效,这种疗法不仅能显著改善风团大小数量,还能减轻患者的皮肤瘙痒程度,更重要的是治疗后少有复发和药物不良反应,对于患者来说更安全、可信赖。

Objective： To study the clinical effect of Modified Xiaofeng powder in treating chronic urticaria. Methods： 106 patients with chronic urticaria treated in our hospital from February 2014 to May 2016 were randomly divided into two groups, with 53 cases in the experiment group and 53 cases in the control group. The control group received Cetirizine Hydrochloride Tablets treatment while the experiment group received Modified Xiaofeng powder, the reaction of patients after treatment was observed and recorded in the experimental process, the size, number and existing time of wheal in patients, the degree of skin itching, adverse reaction and recurrence rate of two groups were compared. Results： The analysis of the experimental results showed that the existing time, size of wheal in patients and the degree of skin itching were relieved after treatment, the relief of the experiment group was significantly better than that of the control group, the difference in adverse reaction and recurrence rate of two groups was significant （P 〈 0.05）. Conclusion： Compared with western medicine treatment, of which Cetirizine Hydrochloride Tablet was a representative, Modified Xiaofeng powder had better clinical effect in treating chronic urticaria, it could decrease the the size and number of wheal in patients, reduce the the degree of skin itching, in addition, it had less adverse reaction and low recurrence rate, which was safer and more reliable to patients.