3580例血清标本梅毒抗体检测结果分析

Analysis of the detection results of syphilis antibody in 3580 cases of serum samples

目的了解神木县人群梅毒的总体感染率和不同年龄、性别人群感染率的差异。方法对本院2013～2014年3580例门诊及住院患者，分别按年龄（19～39岁、40～60岁）和性别（男、女）进行分组，再对其血清标本先以ELISA法进行梅毒抗体检测再以TPPA法进行确认。结果3580例血清标本，以ELISA法检出阳性72例，阳性率2．01％，以TPPA法确认阳性65例，阳性率1．81％；19～39岁年龄组1800例标本，以ELISA法检出阳性36例，阳性率2．0％，以TPPA法确认阳性33例，阳性卒1．83％，40～60岁年龄组1780例标本，以ELISA法检出阳性36例，阳性率2．02％，以TPPA法确认阳性32例，阳性率1．80％，两组结果比较无显著性差异（P〉0．05）；男性组1802例，以ELISA法检出阳性36例，阳性率2．0％，以TPPA法确认阳性33例，阳性率1．83％，女性组1778例，以检出ELISA法检出阳性36例，阳性率2．02％，以TPPA法确认阳性32例，阳性率1．80％，两组结果比较无显著性差异（P〉0．05）。结论神木县梅毒总体感染率偏高，不同年龄、性别间无显著性差异，应加强宣教及防治工作。

Objective To understand the infection rate of syphilis and the difference between the infection rate in different age and gender of Shenmu population. Methods 3580 cases include outpatient and inpatient were grouped according to age （agedlg--39,40--60 years） and gender （male and female） from 2013 to 2014. The syphilis antibody in serum was detected by the method of ELISA first,then confirmed by TPPA method, Results Among the 3 580 cases of serum specimens , 72 cases of positive specimens were detected by the method of ELISA,the positive rate was 2.01% ; 65 cases were confirmed by the method of TPPA,the positive rate was 1.81%. Among the 1 800 cases of serum specimens in 19--39 age group,36 cases of positive specimens were detected by the method of ELISA,the positive rate was 2.0% ; 33 cases were confirmed by the method of TPPA,the positive rate was 1.83%. Among the 1 780 cases of serum specimens in 40--60 age group, 36 cases of positive specimens were detected by the method of ELISA,the positive rate was 2. 02%; 32 cases were confirmed by the method of TPPA,the positive rate was 1.80%. There was no significant difference between the two groups （P〉0.05）. 33 cases of positive specimens were detected by the method of ELISA in 1 802 cases of male group,the positive rate was 2.0% ; 33 cases were confirmed by the method of TPPA,the positive rate was 1. 83M. 36 cases of positive specimens were detected by the method of ELISA in 1 778 cases of female group,the positive rate was 2. 02%. 32 cases were confirmed by the method of TPPA,the positive rate was 1.80%. There was no significant difference between the two groups （P〉0.05）. Conclusion The rate of syphilis infection was high in Shenmu population, there was no significant difference between different age and sex;education and prevention should be strengthened.