2015年某院下呼吸道感染患者细菌分布及耐药特征分析

The Bacterial Distribution And Resistance Analysis Among Lower Respiratory Tract Infection Patients In Our Hospital In 2015

目的通过对本院主要临床科室2015年下呼吸道感染患者痰液，支气管肺泡灌洗液以及血液标本的细菌学研究，揭示本院下呼吸道感染患者细菌分布及耐药特征。方法按照标本类型分为痰液组，灌洗液组、血液组，采用细菌培养分离、鉴定及药敏分析技术，数据纳入whonet5．4数据库，并作相关的统计分析。结果本院下呼吸道感染患者以革兰氏阴性杆菌感染为主，检出率89．6％，肺炎克雷伯菌，大肠埃希菌分列第一、二位，检出率分别为26．9％、20．9％；革兰阳性菌较少，以金黄色葡萄球菌为主，检出率8．5％；多重耐药的铜绿假单胞菌、鲍曼不动杆菌增加趋势明显。结论联合痰液及灌洗液、血液多种标本微生物检测对下呼吸道感染患者的诊治任具有一定意义。切实加强院感监测，严格抗生素的合理应用，防止多重耐药菌进一步扩大的趋势已迫在眉睫。

Objective This article has analyzed the pathogen constituents in the patients and antimierobial resistance pattern with lower respiratory tract infection in five main clinical department of our hospital in 2015. Methods This subject was divided into sputum group, bronchoalveolar lavage fluid group,blood group according to sample types. Baeterias were cultured,isolated patho- genic bacteria,, and then identified,antibiotic resistance anaiysis. The whole datas obtained were analysised by whonet5.4 database. Results Gram negative bacteriums in the patients from lower respiratory tract infection were main pathogens,89.6% in our hospital. Klebsiella Pneumonia was first bacterial, 26.9%. the second was Escherichia Coli, 20.9%. Staphylococcus Aureus was main gram-positive cocci from the patients in lower respiratory tract infection,8.5%. Multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii were increasing obviously. Conclusion It＇s something valuable based on joint detection of sputum,bron-choalveolar lavage fluid and blood in pathogenic microorganism detection. Surveillance of nosocomial infection must be strengthened. Antibiotic standard use must be strict. It＇s imperative to prevent multidrug-resistant bacteria to build something methods in our hospital