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数字PCR技术在临床诊断中的应用进展 被引量:15

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摘要 数字PCR(d PCR)作为核酸检测和定量的新方法,在病原微生物检测、肿瘤相关基因检测、产前诊断等方面应用日益广泛。该文就其在HBV DNA、HIV DNA、表皮生长因子受体(EGFR)突变、异柠檬酸脱氢酶(IDH)突变、胎儿游离DNA等检测中的研究进展作一综述。
出处 《临床检验杂志》 CAS CSCD 2016年第10期785-787,共3页 Chinese Journal of Clinical Laboratory Science
基金 上海市新优青人才计划(XYQ2013095) 上海申康医院发展中心辅助科室能力建设项目(SHDC22014006) 国家自然科学基金项目(81370067 81572061)
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  • 1Daniels G,Finning K,Martin P.Noninvasive fetal blood grouping: present and future. Clinics in Laboratory Medicine . 2010
  • 2Vlková B,Szemes T,Minárik G, et al.Advances in the research of fetal DNA in maternal plasma for noninvasive prenatal diagnostics. Medical Science Monitor . 2010
  • 3Tsui NB,Kadir RA,Chan KC, et al.Noninvasive prenatal diagnosis of hemophilia by microfluidics digital PCR analysis of maternal plasma DNA. Blood . 2011
  • 4Tsui DW,Chiu RW,Lo YD.Epigenetic approaches for the detection of fetal DNA in maternal plasma. Chimerism . 2010
  • 5Nygren AO,Dean J,Jensen TJ, et al.Quantification of fetal DNA by use of methylation-based DNA discrimination. Clinical Chemistry . 2010
  • 6Della Ragione F,Mastrovito P,Campanile C, et al.Differential DNA methylation as a tool for noninvasive prenatal diagnosis (NIPD) of X chromosome aneuploidies. The Journal of Molecular Diagnostics . 2010
  • 7Bustamante-Aragones A,Gonzalez-Gonzalez C,de Alba MR, et al.Noninvasive prenatal diagnosis using ccffDNA in maternal blood: state of the art. Expert Review of Molecular Diagnostics . 2010
  • 8Lo YM,Chiu RW.Noninvasive approaches to prenatal diagnosis of hemoglobinopathies using fetal DNA in ma- ternal plasma. Hematology Oncology Clinics of North America . 2010
  • 9Bellido ML,Radpour R,Lapaire O, et al.MALDI-TOF mass array analysis of RASSF1A and SERPINB5 methy- lation patterns in human placenta and plasma. Biol Re- prod . 2010
  • 10Chu T,Burke B,Bunce K, et al.A microarray-based ap- proach for the identification of epigenetic biomarkers for the noninvasive diagnosis of fetal disease. Prenatal Diagnosis . 2009

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