1Gttrbel P A, Bliden K P, Samara W, et aL Clopidogrel effect on platclet reactivity in patients with stent thrombosis: results of the CRESTStudy[J]; JAm Coil Cardiol, 2005, 46(10): 1827-1832.
2MOiler I, Besta F, Schulz C, et al. Prevalence of clopidogrel non-responders among patients with stable angina pectoris scheduled for elective coronary stent placement[J], Thromb Haemost, 2003, 89(5): 783-787.
3Wiviott S D, Antman E M. Clopidogrel resistance: a new chapter in a fast-moving story[J]. Circulation, 2004, 109(25): 3064-3067.
4Hoffmeyer S, Burk O, von Richter O, et al. Functional polymorphisms of the human mtdtidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo[J]. Proc Natl Acad Sci USA. 2000, 97(7): 3473-3478.
5Mega J L. Close S L. Wiviott S D, et al. Genetic variants in ABCB1 and CYP2C 19 and cardiovascular outcomes after treatment with clopidogrel and prasugrel in the TRITON-TIMI 38 trial: a pharmacogenetic analysis[J]. Lancet, 2010, 376(9749): 1312-1319.
6Wallentin L, James S, Storey R F. et al. Effect of CYP2C 19 and ABCB1 single nucleotide polymorphisms on outcomes of treatment with ticagrelor versus cl0pidogrel for acute coronary syndromes: a genetic substudy of the PLATO trial[J]. Lancet, 2010, 376(9749): 1320-1328.
7Su J, XU J, Li X, et al. ABCB1 C3435T polymorphism and response to clopidogrel treatment in coronary artery disease (CAD) patients: a meta- analysis[J~ PLoS One, 2012, 7(10): 463-466.
8Merali Z, Ross S. Par6 G. The pharmacogenetics of earboxylesterases: CES1 and CES2 genetic variants and their clinical effect[J]. Drug Metabol Drug Interact, 2014, 29(3): 143-151.
9Fukami T, Nakajima M, Maruichi T, et al. Structure and characterization of human carboxylesterase 1A 1, 1A2, and 1 A3 genes[J]. Pharmacogenet Genomics, 2008, 18(10): 911-920.
10Lewis J P, Horenstein R B, Ryan K, et al. The functional G143E variant of carboxylesterase 1 is associated with increased clopidogrel active metabolite levels and greater clopidogrel response[J]. Pharmacogenet Genomics, 2013, 23(1 I: 1-8.
