基于自动左心室容积分析和速度向量成像技术研究正常左心室收缩功能

Lett ventricular analysis and velocity vector imaging in study on normal references of left ventricular systolic function

目的采用自动左心室容积分析(LVA)和速度向量成像技术(VVI)确定左心室射血分数(LVA-EF)、容积指数(LVVI)、整体纵向应变(GLS)的正常值。方法 155名正常人接受常规超声心动图检査,采用机器内置LVA和VVI软件进行图像后处理,获得观测指标:LVA监测舒张末期左心室容积指数(LVEDVI)、收缩末期左心室容积指数(LVESVI)、LVA-EF和VVI监测GLS。结果男性与女性间LVEDVI和LVESVI差异有统计学意义(P均<0.05),而LVAEF和GLS差异无统计学意义(P均>0.05)。男性GLS与年龄呈负相关(r=-0.38,P<0.05);男性与女性受检者中,LVESVI、LVEDVI和LVA-EF与年龄均无相关性(P均>0.05)。传统超声心动图监测的左心室射血分数(Bi-EF)与LVA-EF、GLS与LVA-EF均呈正相关(r=0.35,0.48,P均<0.01),且GLS与LVA-EF的相关性高于Bi-EF与LVA-EF的相关性(P<0.05)。结论本研究通过有限样本量初步分析了LVA和VVI相关指标正常值,其中容积参数受性别影响,应变参数受年龄影响。此外,GLS较传统超声参数(Bi-EF)可更好地反映左心室收缩功能。

Objective To determine normal references of left ventricular ejection traction（LVA-EF）,volume index（LVVI） and global longitudinal strain（GLS） with left ventricular analysis（LVA） and velocity vector imaging（VVI）.Methods Totally 155 normal persons were examed by conventional echocardiography.The needed dynamic images were stored and then post-processes were carried out by LVA and VVI.The relevant data were recorded and analyzed,such as left ventricular end-diastolic volume idex（LVEDVI）,left ventricular end-sistolic volume idex（LVESVI）,LVA-EF by LVA and GLS by VVI.Results The value of LVEDVI and LVESVI had significantly differences between male and female,respectively（both P〈0.05）;while the value of LVA-EF and GLS had no significantly differences（both P〉0.05）.The negative correlation of GLS with age was significantly different only in male group（r=-0.38,P〈0.05）.There were no correlation of age with LVEDVI,LVESVI and LVA-EF in both male and female（P〈0.05）.Conventional echocardiographic left ventricular ejection fraction（Bi-EF） and GLS were both positive correlated with LVA-EF（r=0.35,0.48,both P〈0.01）,and the correlation of GLS with LVA-EF was higher than that of Bi-EF with LVA-EF（P〈0.05）.Conclusion The study through the limited samples draws normal references of LVA and VVI relevant indicators.Volume parameters are affected by gender and strain is affected by age.GLS is a better index on behalf of left ventricular systole function than Bi-EF.