国外痛风治疗指南演变及比较

Evolution of treatment recommendations for gout in abroad

痛风是因长期高尿酸血症导致尿酸盐晶体沉积在关节、肾脏及其他软组织诱发的一组炎症性疾病,且其发病率逐年升高,已成为威胁人们健康的重要疾病。近10年来,相关的国家(组织)根据临床研究证据相继发布了痛风的治疗指南并不断更新。文章对目前国际上广泛采用的治疗指南:2007年英国风湿病学会指南、2012年美国风湿病学会指南、2014年多国专家发布的3e指南和2016年欧洲抗风湿病联盟痛风治疗指南做一比较与总结,为广大临床医生提供参考。

Gout is a group of inflammatory diseases caused by deposition ofurate crystals in the joints, kidneys and other soft tissue due to a long-term hyperuricemia. Gout has become a serious threat to people＇s health, with the prevalence increasing year by year. Over the past 10 years, some countries （organizations） have issued guidelines for treatment of gout based on the clinical research which are constantly updated. In this review, we compared and summarized the current widely-used international treatment guidelines： the 2007 British Society for Rheumatology guidelines, the 2012 American College of Rheumatology guidelines, 2014 multinational expertsissued 3e guidelines and the 2016 European League Against Rheumatism gout treatment guidelines.