儿童过敏性紫癜临床疗效分析及随访

Clinical efficacy analysis and the follow-up survey of the children with Henoch-Schonlein purpura

目的对155例儿童过敏性紫癜的临床疗效及随访结果进行分析,探讨中医药对该病的治疗。方法对2013年4月至2014年3月河南中医药大学第一附属医院儿科收治的155例HSP患儿临床数据进行分析。结果本组患儿男女比例为1.5∶1,以学龄儿童为主;多发于冬春季节;发病诱因以上呼吸道感染为主。均有典型皮肤紫癜,其中伴关节肌肉肿痛54.2%,伴消化道症状46.5%,伴肾损伤6.5%,伴肾炎13.5%。痊愈136例(87.7%),显效13例(8.3%),有效6例(3.9%),无效0例;随访6个月,复发率7.1%。结论中医药治疗小儿过敏性紫癜临床疗效肯定,值得临床推广应用。

Objective To analyze the clinical effects and the follow-up survey of 155 children with Henoch-Schonlein purpura（HSP）,raising awareness of the disease.Methods To retrospectively analyze the clinical data of the 155 cases,who were treated from July 2013 to May 2014 and had been followed up for 6 months.Results The male to female ratio in 155 cases was 1.5 to 1;HSP occurred more commonly in win-ter and spring;most of patients were school-age children;upper respiratory tract infection was the most im-portant predisposing factor.The 155 cases all had the typical skin purpura,and about 54.2% of the patients were with the joint symptoms,46.5% with the digestive tract symptoms,6.5% with renal damage,and 13.5% with nephritis.Of the 155 cases,136 cases（87.7%）were cured;13 cases（8.3%）were remarkably improved,and 6 cases（3.9%）were improved;the treatment was effective in all cases.After 6 months of follow-up,the recurrence rate was 7.1%.Conclusion The clinical effect of traditional Chinese medicine on HSP is positive,and it is worthy of being popularized and applied in pediatric clinics.