哮喘患儿长期吸入糖皮质激素对身高的影响

Effect of long-term inhaled glucocorticoids on height in children with asthma

支气管哮喘（哮喘）是儿童最常见的慢性呼吸道疾病。吸入型糖皮质激素（inhaled corticostcroid，ICS）是目前治疗哮喘最有效的药物，但近来亦有报道长期使用仍会产生一些不利影响。汇总近年来相关文献资料，ICS长期治疗可能会轻度地减缓身高的增长速度，但这种抑制只出现在哮喘治疗早期，并且不影响或仅轻度影响最终身高。ICS对身高的影响，亦与其使用的种类、剂量和吸入方法相关。

Asthma is the most common chronic respiratory disease in children. Currently, inhaled corti- costeroids is the most effective drug for asthma, however, there arc some adverse effect by long-time using. Ac- cording to recent literature, long-time treatment with inhaled corticosteroids may inhibit height growth. But this suppression only occurs within early stage of asthma treatment, and have no effect or slight effect on adult height. The adverse effects of inhaled corticosteroids for height are also related to its iypes, dose and usage.